NCT04164680

Simultaneously PET/MRI in Prolonged DOC Patients

Relationship Between Simultaneously Acquired Resting-state Regional Cerebral Glucose Metabolism and Functional MRI in DOC: a PET/MR Hybrid Scanner Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 24 (actual)
• Sponsor: Hangzhou Normal University · Academic / Other
• Sex: All
• Age: 16 Years – 80 Years
• Healthy volunteers: Accepted

Summary

Recently introduced hybrid PET/MR scanners provide the opportunity to measure simultaneously, and in direct spatial correspondence, both metabolic demand and functional activity of the brain, hence capturing complementary information on the brain's physiological state. Here we exploited PET/MR simultaneous imaging to explore the relationship between the metabolic information provided by resting-state fluorodeoxyglucose-PET (FDG-PET) and fMRI (rs-fMRI) in patients with disorders of consciousness.

Conditions

• Disorder of Consciousness
• Minimally Conscious State
• FDG-PET
• Rs-fMRI

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Multimodal Neuroimaging	fludeoxyglucose (FDG-)PET/MR imaging

Timeline

• Start date: 2018-01-01
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2019-11-15
• Last updated: 2022-07-08

Locations

1 site across 1 country: China