NCT04161313

Respiratory Function, Exercise Capacity and Peripheral Muscle Strength Among Patients With CF, PCD and Healthy Children

Comparison of Respiratory Function, Exercise Capacity and Peripheral Muscle Strength Among Patients With Cystic Fibrosis, Primary Ciliary Dyskinesia and Healthy Children

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 76 (actual)
• Sponsor: Bezmialem Vakif University · Academic / Other
• Sex: All
• Age: 6 Years – 18 Years
• Healthy volunteers: Accepted

Summary

The aim of this study is to compare pulmonary function, respiratory muscle strength, exercise capacity and peripheral muscle strength of patients with CF, PCD and healthy childrens.

Detailed description

The impaired airway clearence and pulmonary functions, exercise intolerance, low physical activity level and decreased peripheral muscle strength make physiotherapy approaches important in the management of CF and PCD.

Conditions

• Primary Ciliary Dyskinesia
• Cystic Fibrosis

Interventions

Type	Name	Description
OTHER	Measurement of functional capacity	Functional capacity of participants will be measured with six-minute walk test.
OTHER	pulmonary function test	It will be measured using basic spirometry and presented lung volume parameters such as FEV1,FVC,FEV1/FVC,PEF, FEF25-75
OTHER	Functional capacity	Functional capacity of participants will be measured with six-minute walk test and sit-to-stand test
OTHER	Peripheral muscle strength	Isometric M. Quadriceps strength will be measured using electronic hand held dynamometer in sitting position.
OTHER	Respiratory muscle strength	Inspiratory and expiratory muscle strength has been assessed by maximal inspiratory and expiratory mouth pressures.

Timeline

• Start date: 2019-12-20
• Primary completion: 2020-02-24
• Completion: 2020-03-12
• First posted: 2019-11-13
• Last updated: 2020-03-18

Locations

1 site across 1 country: Turkey (Türkiye)