Trials / Active Not Recruiting
Active Not RecruitingNCT04161092
The Swedish Study of Liver Transplantation for Non-resectable Colorectal Cancer Metastases
A Randomized Controlled, Open-label, Multicentre Study Evaluating if Liver Transplantation With Liver Grafts From Extended Criteria Donors Not Utilised for Approved Indications Increases Overall Survival in Patients With Non-resectable Isolated Liver Metastases From Colorectal Metastases, in Comparison With Best Alternative Care
- Status
- Active Not Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 45 (estimated)
- Sponsor
- Vastra Gotaland Region · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
To evaluate if the addition of liver transplantation primarily utilizing liver grafts from extended criteria donors not utilized for approved indications to conventional treatment of non-resectable/ non-abatable colorectal liver metastases (CLM) increases overall survival compared to best alternative care.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Liver transplantation Ltx | Patients will be treated with Ltx at Sahlgrenska University Hospital, Göteborg, or Karolinska University Hospital, Huddinge. |
| OTHER | Best alternative care | All available treatments as well as other experimental treatments are tolerated, however no cross-over to other arm will be allowed. |
Timeline
- Start date
- 2020-12-01
- Primary completion
- 2029-12-01
- Completion
- 2030-06-01
- First posted
- 2019-11-13
- Last updated
- 2024-10-28
Locations
2 sites across 1 country: Sweden
Source: ClinicalTrials.gov record NCT04161092. Inclusion in this directory is not an endorsement.