NCT04147091

Nano-hydroxyapatite and Ozone - Effect on Approximal Initial Caries

Influence of Nano-hydroxyapatite and Ozone on Approximal Initial Caries

• Status: Completed
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: Pomeranian Medical University Szczecin · Academic / Other
• Sex: All
• Age: 20 Years – 30 Years
• Healthy volunteers: Accepted

Summary

Objectives: to assess the efficiency of three methods of enamel remineralization on initial approximal caries: 1. a nano-hydroxyapatite gel, 2. gaseous ozone therapy 3. combination of a nano-hydroxyapatite gel and ozone. Materials and Methods: Patients (n=92, age 20-30y) with initial approximal enamel lesions on premolar and molar teeth (n=546) randomly allocated to three groups subjected to a 6-months treatment: Group I: domestic nano-hydroxyapatite remineralizing gel, group II: in-office ozone therapy, group III: both remineralizing gel and ozone therapy. Caries lesions assessed on bitewing radiographs at baseline, after 1 year and after 2 years.

Conditions

• Caries,Dental

Interventions

Type	Name	Description
OTHER	ApaCare & Repair	Initial cariuos lesions were treated.

Timeline

• Start date: 2012-02-01
• Primary completion: 2016-12-01
• Completion: 2016-12-01
• First posted: 2019-10-31
• Last updated: 2019-10-31