NCT04146311

Effect of Short-term Motor Training on Accuracy and Precision of Knee Movement in Human With and Without Knee Pain

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Aalborg University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

The objects of this research are to investigate the ability of the motor learning and test the possible differences between younger and older healthy human, and between non-pain and acute experimental pain and chronic clinical pain conditions.

Detailed description

The project consists of four experimental studies. In the first experiment, younger and older healthy human subjects are involved in a short-term neuromuscular training on the accuracy and precision of knee movement to investigate the possible age effect of the motor learning. The second experiment focuses on the experimental pain on the learning effect of the younger subjects. The third experiment will investigate a group of knee osteoarthritis patients to show the influence of chronic pain on the motor training compared with age-, gender-matched pain free subjects. 3D camera tracking system will be used to record the knee movements at the baseline and after 6-day motor task training. The variability in amplitude of the values of knee movements was transformed to percentage in relation to the target position (accuracy) or to the mean position (precision). The results of the study will contribute to both basic and clinical understanding of the mechanisms related to knee movement control and influences of varies painful conditions.

Conditions

• Isotonic Saline
• Hypertonic Saline
• Healthy Eld Human
• Knee Pain Chronic

Interventions

Type	Name	Description
DRUG	Hypertonic saline	A bolus injection (0.25 ml) of hypertonic saline (5%) into the left infrapatellar fat pad.
DRUG	isotonic saline	A bolus injection (0.25 ml) of isotonic saline (5%) into the left infrapatellar fat pad.
OTHER	Motor training	All the subjects recruited need to have a short-term motor task training at home. 30 times a session, totally 2 sessions a day for 6 days

Timeline

• Start date: 2019-10-30
• Primary completion: 2020-11-28
• Completion: 2020-12-20
• First posted: 2019-10-31
• Last updated: 2021-01-13

Locations

1 site across 1 country: Denmark