NCT04128046

The Effect of Platelet-rich Fibrin Matrix on Skin Rejuvenation

The Effect of Platelet-rich Fibrin Matrix on Skin Rejuvenation: A Split Face Comparison

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 30 (actual)
• Sponsor: New York Medical College · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

Platelet-rich fibrin matrix (PRFM) is made from platelets that are extracted from a patient's blood, and many plastic surgeons and dermatologists have used it to fill in wrinkles and lines on the face. Both patients and doctors have observed that it gives extra volume in these areas and improves overall appearance. However, there is no research that shows how PRFM affects skin quality, such as pores, spots, red areas, and texture. The aim of this study is to determine whether PRFM has a role in rejuvenating facial skin.

Conditions

• Skin Rejuvenation
• Skin Quality
• Wrinkle
• Nasolabial Fold

Interventions

Type	Name	Description
PROCEDURE	PRFM injection	Using a 27-gauge microcannula, a total of 4 mL of PRFM was injected intradermally into the mid-cheek and NLF (2 mL for each site) on one side of the face.
PROCEDURE	Saline injection	Using a 27-gauge microcannula, a total of 4 mL of saline was injected intradermally into the mid-cheek and NLF (2 mL for each site) on the contralateral side of the face.

Timeline

• Start date: 2018-09-03
• Primary completion: 2019-05-28
• Completion: 2019-06-01
• First posted: 2019-10-16
• Last updated: 2019-10-22

Locations

1 site across 1 country: United States