Trials / Unknown
UnknownNCT04127474
Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease
Expression of Trefoil Factors 2 and 3 and Adrenomedullin in Unstimulated Saliva Samples of Chronic Periodontitis Subjects With and Without Coronary Heart Disease
- Status
- Unknown
- Phase
- —
- Study type
- Observational
- Enrollment
- 75 (estimated)
- Sponsor
- Meenakshi Ammal Dental College and Hospital · Academic / Other
- Sex
- All
- Age
- 30 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
To assess the demographic variables, periodontal parameters and to determine the expression of Trefoil factors 2 and 3 and Adrenomedullin in unstimulated saliva samples of periodontally healthy subjects with coronary heart disease and generalised chronic periodontitis subjects with and without coronary heart disease.
Detailed description
A total of 75 subjects will be recruited for the study based on the power of the study. The selected subjects will be divided into 3 groups based on inclusion and exclusion criteria. GROUP I:25Generalized chronic periodontitis subjects without coronary heart disease. GROUP II: 25Generalized chronic periodontitis subjects diagnosed with coronary heart disease. GROUP III: 25Periodontally healthy subjects diagnosed with coronary heart disease. Demographic variables, periodontal parameters and biochemical parameters will be measured in all three groups
Conditions
Timeline
- Start date
- 2019-10-14
- Primary completion
- 2020-12-20
- Completion
- 2021-11-20
- First posted
- 2019-10-15
- Last updated
- 2020-09-02
Locations
1 site across 1 country: India
Source: ClinicalTrials.gov record NCT04127474. Inclusion in this directory is not an endorsement.