NCT04115176

GCF IL-17 Levels and Oxidative Status of Smoking and Non-smoking Individuals With Periodontitis

Smoking Effects on GCF GCF IL-17A AND IL-17 Levels and Oxidative Status of Patients Receiving Periodontal Treatment

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 30 (actual)
• Sponsor: Ondokuz Mayıs University · Academic / Other
• Sex: All
• Age: 35 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study was performed to evaluate the effects of both periodontal treatment and smoking on the gingival crevicular fluid(GCF) levels of interleukin (IL)-17A, IL-17E, Total oxidative stress(TOS) and total antioxidant capasity(TAOC) in smoking and non-smoking patients with severe chronic periodontitis. Systemically healthy 15 smoker,15 non-smoker with chronic periodontitis were attended for the study. Periodontal status were determined by recording periodontal clinical measurements. GCF samples were collected at the baseline, at the end of initial periodontal treatment and 4 weeks after periodontal flap surgery. The data were tested statistically by the Student t and paired sample t tests.

Conditions

• Chronic Periodontitis
• Smoking, Cigarette

Timeline

• Start date: 2017-10-10
• Primary completion: 2019-07-10
• Completion: 2019-07-10
• First posted: 2019-10-03
• Last updated: 2019-10-04

Locations

1 site across 1 country: Turkey (Türkiye)