Clinical Trials Directory

Trials / Completed

CompletedNCT04109417

Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery

Effect of Platelet-Rich Plasma Biomembrane on Enhancing Bone Regeneration Following Endodontic Surgery:A Prospective Randomized Clinical Trial

Status
Completed
Phase
N/A
Study type
Interventional
Enrollment
15 (actual)
Sponsor
Alexandria University · Academic / Other
Sex
All
Age
20 Years – 45 Years
Healthy volunteers
Not accepted

Summary

This study was conducted to evaluate clinical and radiographical outcome of using a standardized platelet-rich plasma (PRP) biomembrane following endodontic surgery and its correlation with the growth factors content in this concentrate.

Detailed description

15 healthy patients of both genders, between 20 and 45 years of age, presenting with 22 anterior/premolar teeth in need of endodontic surgery were recruited. Teeth presented with failed non-surgical root canal therapy and periapical radiolucency of ≥ 1cm in size. Patients were randomly divided following surgery into two groups, with 11 teeth each.

Conditions

Interventions

TypeNameDescription
PROCEDUREosteotomy filled with PRP-gel and covered with PRP-biomembrane
PROCEDUREosteotomy site following the surgical intervention was left empty

Timeline

Start date
2014-11-24
Primary completion
2017-09-12
Completion
2017-10-12
First posted
2019-09-30
Last updated
2019-09-30

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT04109417. Inclusion in this directory is not an endorsement.