NCT04105868

Adolescent Attention to Emotion Study

Visuocortical Dynamics of Affect-Biased Attention in the Development of Adolescent Depression

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: University of Pittsburgh · Academic / Other
• Sex: Female
• Age: 13 Years – 15 Years
• Healthy volunteers: Accepted

Summary

Rates of depression increase rapidly during adolescence, especially for girls, and, thus, research is needed to spur the development of novel interventions to prevent adolescent depression. This project seeks to determine if a novel visuocortical probe of affect-biased attention (i.e., steady-state visual evoked potentials derived from EEG) can 1) be used to prospectively predict depression using a multi-wave repeated measures design and 2) modify affect-biased attention and buffer subsequent mood reactivity using real time neurofeedback. This work could ultimately lead to improved identification of adolescents who are at high risk for depression and directly inform the development of mechanistic treatment targets to be used in personalized intervention prescriptions for high-risk youth.

Conditions

• Depression

Interventions

Type	Name	Description
OTHER	Neurofeedback	Participants will receive feedback during a computerized task that is based on their own visuocortical activity evoked by attention to negative distractors and task-relevant stimuli on the computer screen.

Timeline

• Start date: 2019-10-16
• Primary completion: 2024-09-23
• Completion: 2025-03-30
• First posted: 2019-09-26
• Last updated: 2025-11-13
• Results posted: 2025-11-13

Locations

1 site across 1 country: United States