Trials / Completed
CompletedNCT04103801
Substance P as a Biomarker to Evaluate the Reduction of Multiple Immunization Pain
Substance P as a Biomarker to Evaluate the Reduction of Multiple Immunization Pain Among Infants and Toddlers: A Randomized Controlled Trial
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 132 (actual)
- Sponsor
- Jordan University of Science and Technology · Academic / Other
- Sex
- All
- Age
- 10 Months – 18 Months
- Healthy volunteers
- Accepted
Summary
Immunization is one of the most significant preventive health measures in reducing morbidity and mortality caused by infectious diseases. Studies have shown that Sucrose is recommended to reduce pain associated with vaccination in neonates. The main aim of the study was to determine the effectiveness of sucrose in reducing infant's pain outcomes during immunization among 10-24 month-old infants and toddlers.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Sucrose | Participants in the intervention group were given 2 ml dose of 50% sucrose solution and participants in the placebo group were given 2 ml dose of sterile water. Both groups were administered slowly over 30 seconds sublingually via needle-less syringe immediately prior to the immunization injections. |
Timeline
- Start date
- 2017-07-14
- Primary completion
- 2017-12-20
- Completion
- 2018-04-03
- First posted
- 2019-09-25
- Last updated
- 2019-09-25
Locations
1 site across 1 country: Jordan
Source: ClinicalTrials.gov record NCT04103801. Inclusion in this directory is not an endorsement.