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CompletedNCT04103333

Angelman Syndrome (AS) Biomarker Study

A Study to Explore Cerebrospinal Fluid and Blood Biomarkers in Participants With Angelman Syndrome

Status
Completed
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
20 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
50 Years
Healthy volunteers
Not accepted

Summary

The primary objective of this study is to measure ubiquitin-protein ligase E3A (UBE3A) protein levels in cerebrospinal fluid (CSF) and to evaluate its utility as a biomarker in support of the development of therapies for AS.

Conditions

Interventions

TypeNameDescription
PROCEDURELumbar PunctureAdministered as specified in the treatment arm.
PROCEDUREBlood CollectionAdministered as specified in the treatment arm.

Timeline

Start date
2019-12-18
Primary completion
2022-01-02
Completion
2022-01-02
First posted
2019-09-25
Last updated
2022-01-28

Locations

5 sites across 1 country: United States

Source: ClinicalTrials.gov record NCT04103333. Inclusion in this directory is not an endorsement.

Angelman Syndrome (AS) Biomarker Study (NCT04103333) · Clinical Trials Directory