NCT04097210

Decision-making - the Benefit of Bedside CRP Within Ambulance Care

When Triage is Insufficient - the Benefit of Bedside CRP Within Ambulance Care

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 110 (actual)
• Sponsor: Helsinki University Central Hospital · Academic / Other
• Sex: All
• Age: 16 Years – 104 Years
• Healthy volunteers: —

Summary

Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective. The bedside point-of-care measurements are CRP, lactate acid and suPAR (Soluble Urokinase Plasminogen Activator Receptor). Elevated values associate with the probability of critical illness and predict a risk of death.

Detailed description

Purpose: To improve identification and proper prioritization of patients with non-specific symptoms prehospitally, we intend to investigate whether Q-CRP, a rapid test for CRP, correlates with time-critical states in the above-mentioned patient group alone or together with CRP, lactate and suPAR. The primary endpoint is need for hospital care. Material: Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room. Method: In patients with unspecified conditions, defined according to the inclusion template, a venous blood sample was taken prehospitally at the scene by the EMS. Analysis: Significance tests and regression analyzes with 95% CI were used. The diagnostic accuracy of Q-CRP, lactate, suPAR and combinations thereof were compared with optimal boundary values.

Conditions

• Critical Illness

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	POC

Timeline

• Start date: 2016-01-01
• Primary completion: 2021-06-01
• Completion: 2021-06-01
• First posted: 2019-09-20
• Last updated: 2022-01-31