NCT04084899

The Effect of CPAP on Lung Hyperinflation in Patients With OSA

The Effect of Continuous Positive Airway Pressure Therapy on Lung Hyperinflation in Patients With Obstructive Sleep Apnoea

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: University Hospital Olomouc · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Assessment of the lung hyperinflation by bodypletysmography in patients with obstructive sleep apnoea treated with continuous positive airway pressure therapy.

Detailed description

Rationale: Obstructive sleep apnoea (OSA) is characterized by repetitive closure of upper airways leading to apnoea (complete airflow cessation) or hypopnoea (airflow limitation \> 50% + blood oxygen desaturation \> 3% or airflow limitation \> 30% blood oxygen desaturation \> 4%). The prevalence of lung hyperinflations in sleep apnoea patients and effect of continuous positive airway pressure (CPAP) therapy is not known. Process: Subjects included in the study will be obstructive sleep apnoea (OSA) patients diagnosed by respiratory polysomnography performed in the Sleep Laboratory, Department of Respiratory Medicine, University Hospital Olomouc. Bodypletysmography will be performed in the time of OSA diagnosis and after 3 months of CPAP therapy. Data will be statistically evaluated after completion of the target number of subjects.

Conditions

• Obstructive Sleep Apnea

Interventions

Type	Name	Description
DEVICE	Continuous Positive Airway Pressure therapy	Standard treatment with continuous positive airway pressure

Timeline

• Start date: 2019-09-05
• Primary completion: 2020-01-09
• Completion: 2020-01-09
• First posted: 2019-09-10
• Last updated: 2020-01-13

Locations

1 site across 1 country: Czechia