NCT04078594

Electronic Early Notification of Sepsis in Hospitalized Ward Patients

Stepped-wedge Cluster Randomized Controlled Trial of Electronic Early Notification of Sepsis in Hospitalized Ward Patients (SCREEN)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 65,250 (actual)
• Sponsor: King Abdullah International Medical Research Center · Academic / Other
• Sex: All
• Age: 14 Years
• Healthy volunteers: Not accepted

Summary

Screening for sepsis has been recommended by the Surviving Sepsis Campaign Clinical Practice Guidelines to facilitate early identification and early management of sepsis. However, the optimal tool remains unknown.The objective of this trial is to examine the effect of an electronic sepsis alert tool on reducing hospital mortailty in patients admitted to medical-surgical-oncology wards.

Detailed description

The study aims to examine the effect of screening for sepsis using an electronic sepsis alert versus no alert in hospitalized patients admitted to wards using an active sepsis alert system compared with wards with no active (masked) sepsis alert system on hospital mortality by day 90. The wards will be randomized in a stepped-wedge cluster fashion.

Conditions

• Sepsis

Interventions

Type	Name	Description
OTHER	sepsis e-alert	At 2-each month interval, the e-alert will be activated in five new randomly selected wards, until all wards eventually will have active alert

Timeline

• Start date: 2019-10-01
• Primary completion: 2021-08-30
• Completion: 2022-11-30
• First posted: 2019-09-06
• Last updated: 2023-03-14

Locations

1 site across 1 country: Saudi Arabia