NCT04063202

Development of a Predictive Index for Probable Depression Among Secondary School Students

A Longitudinal Study for Identifying Predictors of Incidence/Remission of Probable Depression and Developing a Predictive Index for Probable Depression Among Secondary School Students

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 4,799 (estimated)
• Sponsor: Chinese University of Hong Kong · Academic / Other
• Sex: All
• Age: 12 Years – 16 Years
• Healthy volunteers: Not accepted

Summary

The present study aims to develop a new predictive index to predict future depression of adolescents by using factors including individual, interpersonal and environmental. The index can be used to predict likelihood of students who are non-probable depression cases convert into probable depression cases. In addition, the investigators also test the factors of depression remission. It can hence be used in school setting to identify high-risk students, and provide them with secondary interventions that are designed by considering modifiable significant variables identified in this unique, large-scale, longitudinal study.

Detailed description

A 12-month longitudinal study will be conducted in secondary school settings. The investigators will investigate incidence of probable depression (i.e., from non-depression, CESD\<16, at baseline to probable depression, CESD≥16, at month 12) and remission of probable depression. The investigators will investigate factors that can prospectively predict new cases/remission of probable depression, including both well-documented risk/protective factors and some under-examined but potentially important local factors (e.g. school/academic stress, psychological resilience). The relative importance of the risk/protective factors at different socio-ecological levels will be compared and their combined effect will be identified. Based on the selected factors, the investigators will derive a new prediction index called the Adolescent Depression Prediction Index (ADPI) in a model building sample and test its performance in predicting incidence of depression in a validation sample among secondary school students in Hong Kong.

Conditions

• Depression
• Stress
• Youth

Interventions

Type	Name	Description
OTHER	Observation	The anonymous structured questionnaire will be self-administered by the participating students in the absence of their teachers in class-room settings.

Timeline

• Start date: 2020-10-30
• Primary completion: 2023-08-01
• Completion: 2023-08-01
• First posted: 2019-08-21
• Last updated: 2022-03-17

Locations

4 sites across 1 country: Hong Kong