Clinical Trials Directory

Trials / Terminated

TerminatedNCT04049578

A Study to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children With Autism Spectrum Disorder

A Phase Ib, Multicenter, Open-Label, 6-Week Study With a 48-Week Extension to Investigate the Pharmacokinetics, Safety, and Tolerability of Balovaptan in Children Ages 2-4 Years With Autism Spectrum Disorder

Status
Terminated
Phase
Phase 1
Study type
Interventional
Enrollment
2 (actual)
Sponsor
Hoffmann-La Roche · Industry
Sex
All
Age
2 Years – 4 Years
Healthy volunteers
Not accepted

Summary

This was a Phase Ib, multicenter, open-label study in children 2-4 years old with autism spectrum disorder (ASD) to investigate the pharmacokinetics, safety, and tolerability of an oral dose of balovaptan once a day (QD). The study was to consists of a 6-week treatment period to evaluate the pharmacokinetics of balovaptan in 2 to 4 year old children followed by an optional extension period of 48 weeks.

Conditions

Interventions

TypeNameDescription
DRUGBalovaptanParticipants were to receive an oral dose of balovaptan once a day (QD) for a 6-week treatment period, followed by an optional extension period of 48 weeks.

Timeline

Start date
2019-12-19
Primary completion
2020-04-23
Completion
2020-05-06
First posted
2019-08-08
Last updated
2020-10-14
Results posted
2020-10-14

Locations

5 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT04049578. Inclusion in this directory is not an endorsement.