NCT03999086

Thromboelastography-Guided Fluid Management in Spinal Surgery

Thromboelastography-guided Fluid Management in Spinal Surgery: A Prospective Analysis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Mayo Clinic · Academic / Other
• Sex: All
• Age: 18 Years – 89 Years
• Healthy volunteers: Not accepted

Summary

The Researchers are trying to evaluate whether using a blood test called thromboelastogram (TEG) to manage patients undergoing multi-level spinal fusion surgery will reduce complications after surgery compared with the standard practices.

Detailed description

Multi-level instrumented spinal fusions represent an important treatment modality for degenerative scoliosis and sagittal malalignment. These surgeries remain a significant physiologic burden with high blood loss and long operative times. Thromboelastography provides a quantitative measure for blood product transfusion surrounding procedures. We aim to utilize thromboelastography to guide transfusions for multi-level spinal instrumentation. This two-arm, randomized, non-blinded prospective analysis will clarify reduced transfusion requirements for TEG-arm compared to non-TEG arm. We will also evaluate postoperative outcomes at the 1 year time-point.

Conditions

• Spinal Fusion

Interventions

Type	Name	Description
PROCEDURE	Intervention	We will utilize thromboelastography to discern when to transfuse blood products in the setting of multi-level spinal fusion
OTHER	Control Group	Laboratory analysis to guide transfusion

Timeline

• Start date: 2018-01-12
• Primary completion: 2019-11-08
• Completion: 2019-11-08
• First posted: 2019-06-26
• Last updated: 2021-02-02

Locations

1 site across 1 country: United States