Trials / Active Not Recruiting
Active Not RecruitingNCT03997435
FOLFOXIRI With or Without Intensification for Rectal Cancer
A Randomized Study of Neoadjuvant Chemoradiotherapy With or Without Intensification With the FOLFOXIRI Chemo-regimen for High-risk Locally Advanced Rectal Cancer
- Status
- Active Not Recruiting
- Phase
- Phase 2
- Study type
- Interventional
- Enrollment
- 72 (actual)
- Sponsor
- CCTU · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Pathologic complete response rate
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Control arm | neoadjuvant concurrent capecitabine-radiotherapy followed by surgery and postoperative chemotherapy. |
| DRUG | Experimental arm | Neoadjuvant FOLFOXIRI x4 cycles, then capecitabine-radiotherapy and postoperative chemotherapy. |
Timeline
- Start date
- 2019-09-10
- Primary completion
- 2026-12-31
- Completion
- 2027-12-31
- First posted
- 2019-06-25
- Last updated
- 2025-11-17
Locations
3 sites across 1 country: Hong Kong
Source: ClinicalTrials.gov record NCT03997435. Inclusion in this directory is not an endorsement.