NCT03996577

Intravenous Infusion of Lidocaine in ERCP

Efficacy of Intravenous Infusion of Lidocaine in Sedation for ERCP: a Randomised Placebo-controlled Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Shandong University · Academic / Other
• Sex: All
• Age: 18 Years – 85 Years
• Healthy volunteers: Accepted

Summary

Intravenous infusion of lidocaine significantly reduces propofol dose for ERCP and improve patients' recovery after ERCP.

Detailed description

This study divide patients into two groups, one will be given lidocaine; another group was given placebo . to observe two groups of patients blood pressure, body movement, and propofol dosage , and the difference in operator satisfaction, and how many people need to give fentanyl again; and two groups of patients after the operation of the reaction, if there are dizziness, nausea, and other adverse reactions; finally, the differences of these two schemes in different populations were analyzed, and the rationalization and individualized medication will be put forward.

Conditions

• Sedation

Interventions

Type	Name	Description
DRUG	Lidocaine	the experimental group will be given 1-1.5mg/kg lidocaine and then 2mg/kg/h
DRUG	placebo	the control group will be given the same volume of saline.

Timeline

• Start date: 2019-05-15
• Primary completion: 2019-10-15
• Completion: 2019-11-15
• First posted: 2019-06-25
• Last updated: 2019-09-23

Locations

2 sites across 1 country: China