Trials / Completed
CompletedNCT03986307
The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling
The Effect of Omega-3 Supplementation on Muscle Functioning, Inflammation and Muscle Signaling in Elderly
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 23 (actual)
- Sponsor
- KU Leuven · Academic / Other
- Sex
- All
- Age
- 65 Years – 100 Years
- Healthy volunteers
- Accepted
Summary
Elderly are supplemented with either Omega-3 (3 x 1.1g per day) or placebo (corn oil) during 14 weeks. The last 12 weeks, supplementation is combined with resistance exercise training (3x per week) focusing on upper leg strength. In the present project, the investigators study whether differences in muscle strength and/or muscle mass between conditions can be explained by omega-3-induced effects on systemic or muscle inflammatory signaling, or differences in muscle molecular signaling.
Detailed description
Elderly are supplemented with either Omega-3 (3 x 1.1g per day) or placebo (corn oil) during 14 weeks. The last 12 weeks, supplementation is combined with resistance exercise training (3x per week) focusing on upper leg strength. In the present project, the investigators study whether differences in muscle strength and/or muscle mass between conditions can be explained by omega-3-induced effects on systemic or muscle inflammatory signaling, or differences in muscle molecular signaling.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Omega-3 polyunsaturated fatty acid supplementation | Daily supplementation with omega-3 capsules (daily for 14 weeks). Each day: 3 capsules of 1.1g |
| OTHER | Resistance exercise | Resistance exercise training in both supplementation conditions (3 times per week for 12 weeks). |
| DIETARY_SUPPLEMENT | Placebo - appearance-matched oil supplementation | Daily supplementation with placebo capsules (daily for 14 weeks). Each day: 3 capsules of 1.1g |
Timeline
- Start date
- 2019-01-01
- Primary completion
- 2019-05-25
- Completion
- 2019-05-25
- First posted
- 2019-06-14
- Last updated
- 2019-06-14
Locations
1 site across 1 country: Belgium
Source: ClinicalTrials.gov record NCT03986307. Inclusion in this directory is not an endorsement.