NCT03983889

Sedation Strategies for Diagnostic Bronchoscopy 2

The Effect and Safety of Different Sedation Strategies for Diagnostic Bronchoscopy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Changhai Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

Diagnostic bronchoscopy is an invasive procedure performed to diagnose respiratory diseases. But pain has been complained by most of the patients receiving such procedures. Sedation or anesthesia was required by both of the patients and bronchoscopists. Unfortunately, no consensus has been made upon the sedation strategies. Multiple sedation approaches have been applied, such as midazolam and fentanyl, remifentanil and propofol, dexmedetomidine and propofol. The present study was designed to compare these protocols in sedation for diagnostic bronchoscopy.

Conditions

• Bronchoscopy
• Sedation

Interventions

Type	Name	Description
DRUG	Midazolam	Midazolam is used as a common medication for sedation in all groups.
DRUG	Fentanyl	Fentanyl is another opioid drug used for analgesia to prevent bronchoscopy induced cough.
DRUG	Dexmedetomidine	Dexmedetomidine is used for sedation in bronchoscopy with less impact on respiration.
DRUG	Remifentanil	Remifentanil is used for analgesia to prevent bronchoscopy induced cough.
DRUG	Propofol	Propofol is used for sedation with high efficacy but more side effect on respiration than dexmedetomidine.

Timeline

• Start date: 2019-06-17
• Primary completion: 2019-11-30
• Completion: 2019-12-31
• First posted: 2019-06-12
• Last updated: 2019-06-14

Locations

1 site across 1 country: China