NCT03980392

South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention

A Randomized Controlled Study to Evaluate Applicability of Korean Multidomain Intervention Program in the South Korean Study to Prevent Cognitive Impairment and Protect Brain Health Through Lifestyle Intervention

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 152 (actual)
• Sponsor: Inha University Hospital · Academic / Other
• Sex: All
• Age: 60 Years – 79 Years
• Healthy volunteers: Accepted

Summary

This study evaluates acceptability and efficacy of multidomain intervention program to prevent cognitive impairment and protect brain health in Korean at-risk elderly. A third of participants will receive facility-based intervention for 6 months, a third will receive home-based intervention for 6 months, and a third is waiting list controls.

Detailed description

Despite extensive research in the field of Alzheimer's disease (AD), no treatment has yet been developed to modify the progression of AD. Therefore, it is important to manage vascular and metabolic risk factors, to eat healthy foods, to exercise, and to participate in social activities to prevent dementia. The FINGER study showed that the multi-domain intervention program is effective to prevent cognitive impairment and disability in elderly. In South Korea, exercise and leisure programs, and brain activity for the elderly also have been conducted in welfare centers and public health centers. However, there are not enough programs that have proven effective in the studies. So the investigators would like to develop a multi-domain intervention program and investigate applicability and efficacy before a large-scale randomized controlled trial.

Conditions

• Mild Cognitive Impairment
• Aged

Interventions

Type	Name	Description
OTHER	Multidomain intervention program	Multidomain intervention program for physical exercise, cognitive training, nutrition, vascular and metabolic risk controls, and motivation

Timeline

• Start date: 2019-05-29
• Primary completion: 2020-02-14
• Completion: 2020-02-25
• First posted: 2019-06-10
• Last updated: 2021-03-04

Locations

6 sites across 1 country: South Korea