Clinical Trials Directory

Trials / Completed

CompletedNCT03969888

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222

A Phase 2 Study of ABBV-3067 Alone and in Combination With ABBV-2222 in Cystic Fibrosis Subjects Who Are Homozygous for the F508del Mutation

Status
Completed
Phase
Phase 2
Study type
Interventional
Enrollment
78 (actual)
Sponsor
AbbVie · Industry
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study will evaluate the safety, tolerability, and efficacy of ABBV-3067 given alone and in combination with various doses of ABBV-2222 in adults with Cystic Fibrosis who are homozygous for the F508del mutation.

Conditions

Interventions

TypeNameDescription
DRUGABBV-3067Tablet taken orally.
DRUGPlacebo ABBV-3067Tablet taken orally.
DRUGABBV-2222Capsule taken orally.
DRUGPlacebo ABBV-2222Capsule taken orally.

Timeline

Start date
2019-12-11
Primary completion
2022-06-09
Completion
2022-06-09
First posted
2019-05-31
Last updated
2023-06-28
Results posted
2023-06-28

Locations

51 sites across 12 countries: United States, Belgium, Canada, Czechia, France, Hungary, Netherlands, New Zealand, Poland, Serbia, Slovakia, United Kingdom

Regulatory

Source: ClinicalTrials.gov record NCT03969888. Inclusion in this directory is not an endorsement.