NCT03957837

Optical Nerve Sheath Changes During Head Down Laparoscopy

Optical Nerve Sheath Diameter Changes During Steep Trendelenburg Position for Laparoscopic Prostatectomy

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 20 (actual)
• Sponsor: ASST Fatebenefratelli Sacco · Academic / Other
• Sex: Male
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Patient undergoing laparoscopic radical prostatectomy in steep trendelenburg position are at risk to develop complication from brain edema. Ultrasound assessment of optical nerve sheath diameter is a simply, non-invasive method to estimate the increase of intracranial pressure. It is unknown how optical nerve sheath diameter changes after prolonged head down position.

Conditions

• Intracranial Hypertension
• Brain Edema
• Pneumoperitoneum
• Surgery, Laparoscopic

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Optical nerve sheath diameter ultrasound measurement	In cases: ultrasound measurement of the diameter of the optical nerve sheath at (T1) baseline before the induction of general anesthesia (5 min after the beginning of mechanical ventilation in supine position); (T2) after 10 min from 25 degrees head down positioning and with pneumoperitoneum insufflation; (T3) after 60 min from T2, in head down position; (T4) after 10 min from tracheal tube removal, in supine position. In healthy controls: ultrasound measurement of the diameter of the optical nerve sheath at (T1) baseline in supine position; (T2) after 10 min from 25 degrees head down positioning; (T3) after 60 min from T2, in a head down position; (T4) after 10 min from positioning supine

Timeline

• Start date: 2019-05-13
• Primary completion: 2019-06-30
• Completion: 2019-07-30
• First posted: 2019-05-21
• Last updated: 2021-01-05

Locations

1 site across 1 country: Italy