NCT03953352

Evaluation of the Automatic Deformable Recontouring on the Daily MVCT for Head and Neck Cancer Adaptive Radiotherapy

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: Institut Claudius Regaud · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This trial is a prospective, monocentric study aiming to evaluate an adaptive radiotherapy method (automatic deformable recontouring on the daily MVCT (MegaVoltage Computerized Tomography)) using the Precise ART™ software in patients with head and neck cancer. Patients will receive helical intensity-modulated radiotherapy (IMRT) according to the standard recommendations (35 fractions during 7 weeks). Radiotherapy will include daily repositioning MVCT. For the study, patients will undergo 4 intermediate re-planning CT-scan (without injection of intravenous contrast agent) at week 3, week 4, week 5 and week 6 of treatment. 3 recontouring modalities will be evaluated for the study: * Manuel recontouring (standard method) * Precise ART™ deformed contours * Precise RTX™ deformed contours The total duration of the study for each patient will be 7 weeks.

Conditions

• Head and Neck Cancer

Interventions

Type	Name	Description
OTHER	Helical intensity-modulated radiotherapy (IMRT)	Helical intensity-modulated radiotherapy (35 fractions, 5 fractions per week) will be administered during 7 weeks: 2 Gy per fraction on tumor and 1.6 Gy per fraction on bilateral lymph node areas.

Timeline

• Start date: 2019-08-01
• Primary completion: 2021-01-01
• Completion: 2021-01-01
• First posted: 2019-05-16
• Last updated: 2026-04-15

Locations

1 site across 1 country: France