Trials / Completed
CompletedNCT03948256
Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage
Danish RAndomized Trial of External Ventricular Drainage Cessation IN Aneurysmal Subarachnoid Haemorrhage (DRAIN)
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 245 (actual)
- Sponsor
- Rigshospitalet, Denmark · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The DRAIN trial is an international multi-centre, 1:1 randomised, parallel-group, superiority clinical trial investigating gradual weaning vs. prompt closure of external ventricular drainage in patients with hydrocephalus following aSAH. The primary objective is to investigate the beneficial and harmful effects of gradual weaning versus prompt closure of EVD treatment in patients with aSAH.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Control intervention | Prompt closure of EVD with subsequent observation period |
| PROCEDURE | Experimental intervention | Gradual weaning of EVD with 5 cmH2O increase in drainage resistance daily until complete closure with subsequent observation period |
Timeline
- Start date
- 2019-06-06
- Primary completion
- 2024-06-18
- Completion
- 2024-06-18
- First posted
- 2019-05-13
- Last updated
- 2024-06-25
Locations
4 sites across 2 countries: Denmark, Norway
Source: ClinicalTrials.gov record NCT03948256. Inclusion in this directory is not an endorsement.