NCT03939936

The Effect of Periodontal Treatment on Psoriasis

Effects of Non-surgical Periodontal Therapy on Inflammatory Markers of Psoriasis

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: Ozge Gokturk · Academic / Other
• Sex: All
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

There is a relationship between psoriasis and periodontal disease. This relationship may be double-sided.

Detailed description

The aim of this randomized controlled clinical study was to determine the effect of non-surgical mechanical periodontal treatment on psoriasis. The study population consisted of 92 periodontitis patients with psoriasis who had untreated periodontal disease. Two randomized groups were formed from these patients. Immediate periodontal treatment (test group, n = 46) and delayed periodontal treatment (control group, n = 46). Clinical periodontal measures, saliva interleukin 2, interleukin 6 and secretory immunoglobulin A levels and PASI scores were performed at baseline and 8th week in control and test group.

Conditions

• Periodontal Diseases

Interventions

Type	Name	Description
OTHER	Psoriatic measurements	Psoriasis Area and Severity Index (PASI) was performed baseline and after 8 weeks. Saliva samples were taken from patients for the evaluation of proinflammatory cytokine baseline and after 8 weeks.
OTHER	Non-surgical periodontal treatment	Non-surgical periodontal treatment was performed baseline and after 8 weeks. Saliva samples were taken from patients for the evaluation of proinflammatory cytokine baseline and after 8 weeks.
OTHER	saliva samples	Saliva samples were taken from patients for the evaluation of proinflammatory cytokine baseline and after 8 weeks.

Timeline

• Start date: 2017-05-01
• Primary completion: 2018-01-30
• Completion: 2018-02-15
• First posted: 2019-05-07
• Last updated: 2019-05-09

Locations

1 site across 1 country: Turkey (Türkiye)