Trials / Completed
CompletedNCT03926273
Serum and Urine Ghrelin in Adult Epileptic Patients
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 80 (actual)
- Sponsor
- Zagazig University · Other Government
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- —
Summary
Several neuropeptides have concerned with epilepsy pathogenesis, ghrelin showed an anticonvulsant effect. There is a potential relation between its level and antiepileptic drugs (AED) response.
Detailed description
Several neuropeptides have concerned with epilepsy pathogenesis, ghrelin showed an anticonvulsant effect. There is a potential relation between its level and antiepileptic drugs (AED) response. Objective: to evaluate ghrelin effect in adult epileptic patients and in response to AED. Methods: This case control study included 40 adult epileptic patients and 40 healthy controls. Participants were subjected to history taking of seizure semiology, full general and neurological examination, electroencephalography and cranial CT or MRI. Fasting serum acylated ghrelin (AG) and unacylated ghrelin (UAG) and urine AG levels were estimated to all participants by enzyme - linked immunosorbent assay (ELIZA).
Conditions
Timeline
- Start date
- 2018-06-01
- Primary completion
- 2019-01-30
- Completion
- 2019-02-05
- First posted
- 2019-04-24
- Last updated
- 2019-04-24
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT03926273. Inclusion in this directory is not an endorsement.