NCT03924102

Cardiac Perfusion and Metabolism With [11C] Acetate PET/CT is Associated With Hematopoietic System Activation in Acute Decompensated Heart Failure: An Imaging Sub-study

• Status: Withdrawn
• Phase: Phase 1
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Alabama at Birmingham · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this sub-study is to use positron emission tomography and computed tomography imaging (PET/CT) with an investigational drug called \[11C\] acetate to see if inflammation in patients with acute decompensated heart failure (ADHF) can cause changes in blood flow and oxygen use in the heart. This study may help physicians better understand how to treat patients diagnosed with ADHF in the future.

Conditions

• Acute Decompensated Heart Failure

Interventions

Type	Name	Description
DRUG	Cardiac Perfusion and Metabolism with [11C] Acetate PET/CT	A rest and stress imaging study will be conducted on the PET/CT scanner with \[11C\] Acetate.

Timeline

• Start date: 2025-12-31
• Primary completion: 2026-10-31
• Completion: 2026-10-31
• First posted: 2019-04-23
• Last updated: 2023-04-07

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study