NCT03922542

Comparison of Standard vs. Accelerated Corneal Crosslinking

Randomized Comparison of Standard vs. Accelerated Corneal Crosslinking for Treatment of Progressive Keratoconus or Ectasia

• Status: Recruiting
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 510 (estimated)
• Sponsor: Price Vision Group · Industry
• Sex: All
• Age: 10 Years
• Healthy volunteers: Not accepted

Summary

The study objective is to compare accelerated and standard corneal crosslinking for treatment of progressive keratoconus or corneal ectasia.

Conditions

• Keratoconus
• Ectasia Corneal

Interventions

Type	Name	Description
COMBINATION_PRODUCT	riboflavin 0.1%	Use of riboflavin 0.1% eye drops and 9 mW/cm2 UVA light for 10 minutes
COMBINATION_PRODUCT	Riboflavin 0.1%	Use of riboflavin 0.1% eye drops and 3 mW/cm2 UVA light for 30 minutes

Timeline

• Start date: 2019-04-16
• Primary completion: 2026-06-01
• Completion: 2026-07-01
• First posted: 2019-04-22
• Last updated: 2025-07-31

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated drug study