Trials / Completed
CompletedNCT03917212
Energy Metabolism in Branched-chain Organic Acidemias
Non-invasive Measurement of Energy Metabolism in Patients With Primary and Secondary Mitochondrial Diseases
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 57 (actual)
- Sponsor
- German Diabetes Center · Academic / Other
- Sex
- All
- Age
- 5 Years
- Healthy volunteers
- Accepted
Summary
Energy metabolism and insulin sensitivity were assessed in a case-control study in patients with branched-chain organic acidemias.
Detailed description
Children and adults with branched-chain organic acidemias and matched healthy humans underwent deep metabolic phenotyping using non-invasive magnetic resonance spectroscopy, oral glucose tolerance tests and measurements of leucocyte respirometry in order to assess changes in energy metabolism and insulin sensitivity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No intervention | No intervention, observational study with metabolic characterisation |
Timeline
- Start date
- 2012-03-01
- Primary completion
- 2017-11-01
- Completion
- 2018-03-01
- First posted
- 2019-04-16
- Last updated
- 2019-04-16
Locations
2 sites across 1 country: Germany
Source: ClinicalTrials.gov record NCT03917212. Inclusion in this directory is not an endorsement.