NCT03864198

To Evaluate the Effect of Reveratrol,Folic Acid, Vitamin D, Vitamin B12 and B6 in Male Infertility

Evaluation of Treatment With Trans-resveratrol, Folic Acid, Vitamin D, Vitamin B12 and B6 in Men With Infertility

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 20 (estimated)
• Sponsor: University Of Perugia · Academic / Other
• Sex: Male
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

The objective of this study is to evaluate the impact of the Genante(TM) on the spermiogram parameters in infertile male patients

Detailed description

This is a single-centre prospective observational study. Twenty infertile male patients. Inclusion criteria are: Age:18-50 years oligozoospermia: \< 5 million spermatozoa/mL; asthenozoospermia: \< 32% progressive motile spermatozoa; teratozoospermia: \< 4% normal forms. Esclusion criteria: Patients with azoospermia, who smoke, use drugs, drugs with proven fertility toxicity, exposed to any environmental or occupational toxic substances, radiation or heat; with orchitis secondary to mumps, sexually transmitted diseases, history of cryptorchidism, previous testicular torsion, genitourinary anomalies, alterations of the epididymis or deferens; and inguinal surgery Pretreatment evaluation included: Semen analysis Hormonal determinations:follicle-stimulating hormone (FSH) and luteinising hormone (LH) total Testosterone Total,estradiol, prolactina, 25-OH-Vitamin D3); scrotal ultrasound prostatic transrectal ultrasound Outocmes measures (baseline, at 1 and 6 months): * Semen volume (mL) * Total sperm number (106/ejaculate) * Sperm concentration (106/mL) * Total motility (PR + NP) * Progressive motility (PR, %) * Vitality (live spermatozoa, %) * Sperm morphology (normal forms, %) * Ph * FSH * LH * Testosterone totale * Estradiol * Prolactiona * 25-OH-Vitamin D3 * scrotal ultrasound * prostatic transrectal ultrasound

Conditions

• Male Infertility

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Genante	A dietary supplement for male infertility

Timeline

• Start date: 2019-01-20
• Primary completion: 2019-03-20
• Completion: 2019-04-30
• First posted: 2019-03-06
• Last updated: 2019-03-06

Locations

1 site across 1 country: Italy