Trials / Terminated
TerminatedNCT03860753
Effects of Pioglitazone on Stress Reactivity and Alcohol Craving (Pilot)
- Status
- Terminated
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 4 (actual)
- Sponsor
- The University of Texas Health Science Center, Houston · Academic / Other
- Sex
- All
- Age
- 21 Years – 40 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to assess the effect of pioglitazone on stress- and alcohol-related measures in treatment-seeking individuals with alcohol use disorder (AUD) and elevated levels of stress and anxiety.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Pioglitazone | For the current trial we will follow recommended adult initial dosing at 30 mg/d to reach maintenance dose of 45 mg/d by week 2, which is within standard titration parameters as per the investigator's brochure. |
| DRUG | Placebo | Pill capsules will look same as that of active drug. |
Timeline
- Start date
- 2019-03-01
- Primary completion
- 2019-08-23
- Completion
- 2019-08-23
- First posted
- 2019-03-04
- Last updated
- 2020-10-26
- Results posted
- 2020-10-26
Locations
1 site across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03860753. Inclusion in this directory is not an endorsement.