NCT03855527

Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth

Effectiveness of Silver Diamine Fluoride as Cavity Disinfectant After Atraumatic Restorative Treatment in Primary Teeth: A Randomized Clinical Trial

• Status: Completed
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Nourhan M.Aly · Academic / Other
• Sex: All
• Age: 4 Years – 6 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to evaluate the effectiveness of silver diamine fluoride (SDF) compared to chlorhexidine (CHX) as a cavity disinfectant in primary molars after Atraumatic Restorative Treatment approach (ART).

Detailed description

This study is a three arm randomized controlled clinical trial, where children with an age range of 4-6 years indicated for Atraumatic Restorative Treatment (ART) are selected from the outpatient clinic of Pediatric Dentistry and Public Health Department, Faculty of Dentistry, Alexandria University after securing necessary consents. Sixty teeth are randomly allocated into 3 groups of Atraumatic restorative treatment approaches. Group I is assigned to silver diamine fluoride as an antibacterial agent, Group II is assigned to chlorhexidine as an antibacterial agent, and Group III serves as a negative control.

Conditions

• Dental Caries

Interventions

Type	Name	Description
DRUG	Silver Diamine Fluoride	SDF will be applied as a cavity disinfected after atraumatic restorative technique (Antimicrobial effect)
DRUG	Chlorhexidine	Chlorhexidine will be applied as a cavity disinfected after atraumatic restorative technique (Antimicrobial effect)
PROCEDURE	Atraumatic Restorative Treatment without Disinfection	Atraumatic Restorative Technique will be performed without cavity disinfection

Timeline

• Start date: 2018-01-12
• Primary completion: 2019-01-18
• Completion: 2019-03-20
• First posted: 2019-02-26
• Last updated: 2020-04-10

Locations

1 site across 1 country: Egypt