NCT03853174

Exercise Training and Inflammatory Mediators in COPD

Effect of Exercise Training on Inflammatory Mediators in COPD

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 28 (actual)
• Sponsor: Faculty of Medicine, Sousse · Academic / Other
• Sex: Male
• Age: 40 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020\[1\]. COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversable\[2\].

Detailed description

Chronic obstructive pulmonary disease (COPD) is widely spread all over the world. It is predicted to be the third leading cause of death by 2020. COPD is a common, preventable treatable disease that is characterized by an airflow limitation which is not fully reversable.Not only the long-term exposition to noxious particles and gases contributes to the development of COPD, but also so many others factors such as genetics and cigarette smoking. It has been shown that cigarettes are harmful and contributed to different extra pulmonary disorders. Indeed, it induced a systemic inflammation that was considered as a key process in the pathogenesis of COPD and triggered the activation of inflammatory cells and an abnormal increase of circulating cytokines such as CRP, interleukin (IL6), IL8, tumor necrosis factor alpha (TNF alpha) and leptin.

Conditions

• COPD

Interventions

Type	Name	Description
OTHER	Endurance Training ET	Endurance training were prformed. Intensity was gradually increased.
OTHER	Resistance Training RT	Resistance training were prformed. Intensity was gradually increased.

Timeline

• Start date: 2019-01-01
• Primary completion: 2019-04-17
• Completion: 2019-04-27
• First posted: 2019-02-25
• Last updated: 2019-12-20

Locations

1 site across 1 country: Tunisia