NCT03847155

Prevention of Nicotine Abstinence in Critically Ill Patients After Major Surgery

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 52 (actual)
• Sponsor: University Hospital Ostrava · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The primary objective of this study is to determine whether the application of transdermal nicotine patches in critically ill patients after major surgery with nicotine abstinence condition is associated with a lower incidence of delirium.

Detailed description

Patients in a group with medical intervention receive nicotine patch within 24 hours after surgery. The nicotine patch is replaced every day. Delirium is evaluated every day by the Confusion Assessment Method (CAM) - ICU test. The maximum length of intervention is 7 days. Patients in a group with placebo receive a placebo patch within 24 hours after surgery. This patch is replaced every day. Delirium is evaluated in the same way - CAM - ICU test. The maximum length of the placebo intervention is 7 days.

Conditions

• Nicotine Dependence

Interventions

Type	Name	Description
DRUG	Nicotine patch	The patients will receive a nicotine patch for the period of a maximum of 7 days.
OTHER	Placebo patch	The patients will receive a placebo patch for the period of a maximum of 7 days.

Timeline

• Start date: 2015-09-23
• Primary completion: 2021-01-31
• Completion: 2021-02-08
• First posted: 2019-02-20
• Last updated: 2021-02-09

Locations

1 site across 1 country: Czechia