NCT03839563

Temporal Relations and Exercise Interventions of Various Gait and Cognitive Domains in Older Adults

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 189 (estimated)
• Sponsor: Taipei Medical University · Academic / Other
• Sex: All
• Age: 65 Years – 100 Years
• Healthy volunteers: Accepted

Summary

The effectiveness of conventional exercise, tai chi chuan and health education/usual physical activity over a 6-month intervention period in improving primary outcomes and secondary outcomes in older mild cognitive impairment adults will be compared. Third, whether changes in serum levels of the brain-derived neurotrophic factor (BDNF), insulin-like growth factor (IGF)-1, and vascular endothelial growth factor (VEGF) and expression of the apolipoprotein E (APOE) ε4 allele parallel changes in gait characteristics and cognitive functions after the intervention will be examined.

Conditions

• Fallers
• Mild Cognitive Impairment

Interventions

Type	Name	Description
BEHAVIORAL	Exercise	Each session will last 60 min, consisting of 10 min of warm-up, 45 min of exercise, and a 5-min cool-down.

Timeline

• Start date: 2019-02-15
• Primary completion: 2023-12-31
• Completion: 2023-12-31
• First posted: 2019-02-15
• Last updated: 2022-09-29

Locations

1 site across 1 country: Taiwan