Trials / Terminated
TerminatedNCT03818542
A Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma
A Phase 1b Multi-Center Pharmacodynamic Study to Assess the Effects of Multiple Study Drug Regimens in Subjects With Newly Diagnosed Locally Advanced Head and Neck Squamous Cell Carcinoma
- Status
- Terminated
- Phase
- Phase 1
- Study type
- Interventional
- Enrollment
- 3 (actual)
- Sponsor
- AbbVie · Industry
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A study evaluating the safety, pharmacokinetics, and biomarker profiles of multiple study drugs as monotherapy in subjects with newly diagnosed, treatment-naïve locally advanced squamous cell carcinoma of the head and neck who are candidates for surgical resection.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | ABBV-181 | intravenous infusion |
| DRUG | ABBV-368 | intravenous infusion |
| DRUG | ABBV-927 | intravenous infusion |
| DRUG | ABBV-927 | intratumoral injection |
Timeline
- Start date
- 2020-01-22
- Primary completion
- 2020-09-23
- Completion
- 2020-09-23
- First posted
- 2019-01-28
- Last updated
- 2020-12-31
Locations
3 sites across 1 country: United States
Regulatory
- FDA-regulated drug study
Source: ClinicalTrials.gov record NCT03818542. Inclusion in this directory is not an endorsement.