Clinical Trials Directory

Trials / Completed

CompletedNCT03816306

Six Months Clinical and Echocardiographic Outcome of ARNI LCZ696 Therapy in HFrEF Patients

Six Months Clinical and Echocardiographic Outcome of Angiotensin Receptor-Neprilysin Inhibitor (ARNI) LCZ696 Therapy in Heart Failure Patients With Reduced Ejection Fraction (HFrEF)

Status
Completed
Phase
Study type
Observational
Enrollment
100 (actual)
Sponsor
Mohammed Alnims · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

To evaluate the clinical and echocardiographic outcome of LCZ696 therapy in HFrEF (NYHA Class II - IV and EF =≤ 40%).patients, in addition to the efficacy of LCZ696 in reducing mortality and rehospitalisation rate.

Conditions

Interventions

TypeNameDescription
DRUGLCZ 696LCZ696 is an Angiotensin receptor neprilysin inhibitor. It's composed of Sacubitril/Valsartan. LCZ696 starting dose 50 mg P.O. BID, LCZ696 100 mg P.O. BID and up-titration to LCZ696 200 mg P.O. BID.

Timeline

Start date
2018-06-01
Primary completion
2019-12-01
Completion
2019-12-01
First posted
2019-01-25
Last updated
2020-01-18

Locations

1 site across 1 country: Egypt

Regulatory

Source: ClinicalTrials.gov record NCT03816306. Inclusion in this directory is not an endorsement.