NCT03791866

The Th9/IL-9 and Early Enteral Nutrition in Sepsis

The Roles of Th9/IL-9 in the Mechanisms of Early Enteral Nutrition Maintaining Intestinal Mucosal Barrier in Sepsis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Nanjing First Hospital, Nanjing Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators aim to evaluate the roles of Th9/IL-9 in the mechanisms of early enteral nutrition (EEN) maintaining intestinal mucosal barrier in sepsis. The results of this study would lay the foundation for revealing the mechanisms of EEN improving immune imbalance of sepsis and provide a new idea to the early treatment of sepsis. In addition, the investigators also aim to evaluate the effects of different proportions of target total enteral nutrition on the prognosis of sepsis.

Conditions

• Sepsis
• Intestinal Mucosal Barrier
• Th9 Cells
• Enteral Nutrition

Interventions

Type	Name	Description
OTHER	Nutrition	Enteral nutrition

Timeline

• Start date: 2018-10-01
• Primary completion: 2019-12-31
• Completion: 2020-06-30
• First posted: 2019-01-03
• Last updated: 2019-01-03

Locations

1 site across 1 country: China