Trials / Completed
CompletedNCT03789565
Hepcidin Levels in Periodontal Health and Disease
Gingival Crevicular Fluid and Serum Levels of Hepcidin, IL-6 and IL-10 in Periodontal Health and Disease
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 90 (actual)
- Sponsor
- Bulent Ecevit University · Academic / Other
- Sex
- All
- Age
- 32 Years – 52 Years
- Healthy volunteers
- —
Summary
Periodontal disease refers to inflammatory disease of the periodontium caused by the host and/or pathogenic microorganisms. Anti-inflammatory and pro-inflammatory cytokines play a role in the periodontal inflammation process. The aim of this study was to evaluate the levels of hepcidin, interleukin (IL)-6, and IL-10 levels in gingival crevicular fluid (GCF) and in serum samples obtained from individuals with periodontal inflammation.
Detailed description
The study included 90 individuals, who were divided into three groups: periodontally healthy (PH) (n=30); gingivitis (G) (n=30); and chronic periodontitis (CP) (n=30). GCF and serum samples were obtained from each individual, and samples were evaluated using ELISA. Statistical evaluation of the data was performed using the SPSS packet data program.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Biomarker test | Diagnostic biomarker study |
Timeline
- Start date
- 2017-03-15
- Primary completion
- 2018-01-20
- Completion
- 2018-02-15
- First posted
- 2018-12-28
- Last updated
- 2019-10-04
Locations
1 site across 1 country: Turkey (Türkiye)
Source: ClinicalTrials.gov record NCT03789565. Inclusion in this directory is not an endorsement.