NCT03789357

Prevalence of Primary Aldosteronism in Patients With Stroke

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 300 (actual)
• Sponsor: Changi General Hospital · Academic / Other
• Sex: All
• Age: 21 Years – 80 Years
• Healthy volunteers: —

Summary

Strokes leads to significant morbidity and mortality, and hypertension is the most important risk factor for strokes. It is estimated that up to 10% of patients with hypertension have the underlying, treatable condition of primary aldosteronism. Hence, we hypothesize that the prevalence of primary aldosteronism is high in patients with strokes, a complication of long-standing hypertension. Patients admitted with an acute stroke to the Acute Stroke Unit, Changi General Hospital, will be screened for Primary Aldosteronism three months post-stroke, and confirmatory tests will be done with saline-infusion test.

Conditions

• Primary Aldosteronism
• Stroke

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Aldosterone renin ratio	Aldosterone Renin Ratio to screen for Primary Aldosteronism

Timeline

• Start date: 2018-05-01
• Primary completion: 2021-07-31
• Completion: 2021-09-30
• First posted: 2018-12-28
• Last updated: 2022-05-20

Locations

1 site across 1 country: Singapore