Trials / Withdrawn
WithdrawnNCT03783468
LIght Sedation Pressure Support
Early LIght Sedation Pressure Support in ARDS Patients
- Status
- Withdrawn
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 0 (actual)
- Sponsor
- University Hospital, Lille · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Sedation may have many drawbacks in ICU patients: cardiovascular, neurologic, muscular. Light sedation and Pressure Support ventilation is feasible in ARDS patients. However spontaneous breathing can lead to high transpulmonary pressure. The goal of the study is to measure transpulmonary pressure before sedation decrease and after stabilization. The main endpoint is transpulmonary pressure less than 24 cmH2O.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | decrease of sedation doses and switch of ventilator settings | tapering sedation doses (propofol) switch from assisted ventilation to pressure support ventilation |
Timeline
- Start date
- 2021-12-01
- Primary completion
- 2023-12-01
- Completion
- 2023-12-01
- First posted
- 2018-12-21
- Last updated
- 2022-03-17
Source: ClinicalTrials.gov record NCT03783468. Inclusion in this directory is not an endorsement.