Trials / Terminated
TerminatedNCT03778528
Evaluation of Ocular Lens Proteins in Cataract From Individuals With Down Syndrome
- Status
- Terminated
- Phase
- —
- Study type
- Observational
- Enrollment
- 1 (actual)
- Sponsor
- University of Colorado, Denver · Academic / Other
- Sex
- All
- Age
- 1 Month – 18 Years
- Healthy volunteers
- Not accepted
Summary
This study involves the collection ocular lens tissue from individuals with Down syndrome and age-matched controls at the time of cataract surgery.
Detailed description
Individuals with Down syndrome have an increased rate of cataract. The reason for this increase is unclear. Normally, once cataracts become a significant impairment, an ophthalmologist will determine when cataract surgery should be performed. When this surgery is performed, cataractous tissues are cut out and discarded with medical waste. In this study, these tissue will be collected and protein analysis performed to determine what changes in different proteins are found in Down syndrome lenses as compared to normal cataractous lenses.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | cataract surgery | tissue collection. |
Timeline
- Start date
- 2018-05-30
- Primary completion
- 2020-07-01
- Completion
- 2020-07-01
- First posted
- 2018-12-19
- Last updated
- 2020-07-07
Locations
1 site across 1 country: United States
Source: ClinicalTrials.gov record NCT03778528. Inclusion in this directory is not an endorsement.