Trials / Active Not Recruiting
Active Not RecruitingNCT03777384
EValuating the Safety Of De-escaLated Head and Neck Irradiation in HPV positivE Oropharynx Cancer in Non-smokers/Minimal Smokers
- Status
- Active Not Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 75 (actual)
- Sponsor
- Sanford Health · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
A prospective, observational study evaluating the durability of local/regional control of previously published de-escalated radiotherapy protocols for patients with P16 positive oropharynx cancers who have minimal nicotine exposure who are not current uses (\< 10 pack year smoking history; \< 10 year history of any nicotine product \[electronic cigarette, chewing tobacco\]). Quality of Life measures will also be collected.
Detailed description
This is a prospective, single-site, observational study in head and neck cancer participants. The purpose of this study is to provide a systematic platform to analyze, interpret, and track radiation dose de-escalation therapy and associated participant outcomes from treatments identified by these results. Participants will be asked to complete quality of life questionnaires at regular time points before, during, and after treatment.
Conditions
Timeline
- Start date
- 2018-10-12
- Primary completion
- 2026-07-01
- Completion
- 2026-12-01
- First posted
- 2018-12-17
- Last updated
- 2026-02-06
Locations
2 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT03777384. Inclusion in this directory is not an endorsement.