Clinical Trials Directory

Trials / Terminated

TerminatedNCT03749447

An Extended Access Program for Bardoxolone Methyl in Patients With CKD (EAGLE)

An Extended Access Program to Assess Long Term Safety of Bardoxolone Methyl in Patients With Chronic Kidney Disease

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
270 (actual)
Sponsor
Biogen · Industry
Sex
All
Age
12 Years
Healthy volunteers
Not accepted

Summary

This extended access study will assess the long-term safety and tolerability of bardoxolone methyl in qualified patients with chronic kidney disease (CKD) who previously participated in one of the qualifying clinical studies with bardoxolone methyl. Patients will remain in the study until bardoxolone methyl is available through commercial channels or until patient withdrawal, whichever is sooner.

Conditions

Interventions

TypeNameDescription
DRUGBardoxolone methylBardoxolone methyl capsules

Timeline

Start date
2019-03-08
Primary completion
2023-08-23
Completion
2023-08-23
First posted
2018-11-21
Last updated
2025-06-03
Results posted
2024-03-19

Locations

87 sites across 6 countries: United States, Australia, France, Japan, Puerto Rico, Spain

Regulatory

Source: ClinicalTrials.gov record NCT03749447. Inclusion in this directory is not an endorsement.