NCT03743792

Acute Raspberry Intake on Metabolic Control and Cognitive Function

The Effects of Acute Raspberry Intake on the Relationship Between Enhanced Metabolic Control and Cognitive and Psychomotor Function

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 6 (actual)
• Sponsor: USDA Human Nutrition Research Center on Aging · Federal
• Sex: All
• Age: 55 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The purpose of this project is to determine whether restoring the post-prandial metabolic/inflammatory balance via supplementation with raspberries results in improved cognitive performance, and if these enhancements are mediated through improvements in vascular function.

Detailed description

This study will investigate the effects of red raspberry in a relevant human model of metabolic disturbance to understand the relationship between red raspberry intake, metabolic and immune- balance and cognitive and psychomotor performance in older/over weight adults. A secondary goal of the project is to provide data on central vascular function in relation to metabolic-, inflammatory- and cognitive outcomes. Our primary working hypothesis is that red raspberries will improve metabolic- / inflammatory- balance in older overweight and obese adults resulting in improved cognitive and psychomotor performance mediated in part through improvements in vascular function. Two main objectives have been devised to meet the goals of the project and test our hypotheses: 1) Evaluate the effects of acute dietary raspberry intake on metabolic-associated impairments in cognitive and psychomotor function in overweight/obese adults (55-70y) following a meal challenge. 2) Evaluate the effects of acute dietary raspberry on measures of vascular function

Conditions

• Aging
• Age-related Cognitive Decline
• Obesity

Interventions

Type	Name	Description
DIETARY_SUPPLEMENT	Active breakfast	freeze-dried red raspberry powder (12.5 g) in drink+ freeze-dried red raspberry powder (12.5 g) in buttermilk biscuit sandwich
DIETARY_SUPPLEMENT	Control breakfast	Control drink + buttermilk biscuit sandwich

Timeline

• Start date: 2019-02-01
• Primary completion: 2021-10-01
• Completion: 2023-04-30
• First posted: 2018-11-16
• Last updated: 2023-05-10

Locations

1 site across 1 country: United States