NCT03739476

Clinical Trial With Quetiapine Prophylaxis Postoperative Delirium in High Risk Surgical Patients

Controlled, Double-blind, Randomized Clinical Trial for Prophylaxis of Postoperative Delirium in High Risk Surgical Patients With Quetiapine

• Status: Terminated
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 54 (actual)
• Sponsor: Fundación Instituto de Estudios de Ciencias de la Salud de Castilla y León · Academic / Other
• Sex: All
• Age: 65 Years
• Healthy volunteers: Not accepted

Summary

Double blinded Clinical trial to test efficacy of Quetiapine versus placebo in reducing postoperative delirium in high risk surgical patients after three days of treatment.

Detailed description

This study evaluates postoperative delirium in high risk surgical patients to know the incidence of postoperative delirium in patients at risk, over 65 years, treated early with prophylactic quetiapine versus placebo.

Conditions

• Postoperative Delirium

Interventions

Type	Name	Description
DRUG	Quetiapine 25 milligrams capsule	Compare the incidence of postoperative delirium.
DRUG	Placebo oral capsule	Compare the incidence of postoperative delirium.

Timeline

• Start date: 2019-02-13
• Primary completion: 2020-04-02
• Completion: 2020-06-30
• First posted: 2018-11-13
• Last updated: 2025-05-22

Locations

1 site across 1 country: Spain