NCT03734822

Comparative Analysis of CO2 Monitoring Methods in Patients With CF Undergoing General Anesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 47 (actual)
• Sponsor: Nationwide Children's Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Four methods are routinely used to monitor CO2 in patients. End tidal CO2 (EtCO2) is monitored through the endotracheal tube during general anesthesia. CO2 is also monitored in other healthcare settings transcutaneously (TCO2), via finger stick capillary CO2 (CapCO2), and arterial blood gas (ABG). The purpose of this study is to perform all four measurements simultaneously during general anesthesia to identify which measure provides the most accurate data with the least amount of patient risk.

Conditions

• Cystic Fibrosis

Interventions

Type	Name	Description
OTHER	End tidal CO2 (EtCO2)	End tidal CO2 (EtCO2) is monitored through the endotracheal tube during general anesthesia.
DEVICE	Transcutaneous CO2 (TCO2)	Continuous and noninvasive real-time monitoring of transcutaneous CO2.
DIAGNOSTIC_TEST	Capillary CO2 (CapCO2)	Capillary CO2 collected by finger stick and run on the i-STAT handheld blood analyzer.
DIAGNOSTIC_TEST	Arterial blood gas (ABG)	Arterial blood gas collected from the radial artery and run on the i-STAT handheld blood analyzer.

Timeline

• Start date: 2016-03-10
• Primary completion: 2017-12-20
• Completion: 2017-12-20
• First posted: 2018-11-08
• Last updated: 2019-03-14
• Results posted: 2019-03-14

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study